Basic Mechanical Interactions in Shaker Testing
نویسندگان
چکیده
منابع مشابه
Voltage - dependent Structural Interactions in the Shaker K 1 Channel
Using a strategy related to intragenic suppression, we previously obtained evidence for structural interactions in the voltage sensor of Shaker K 1 channels between residues E283 in S2 and R368 and R371 in S4 (Tiwari-Woodruff, S.K., C.T. Schulteis, A.F. Mock, and D.M. Papazian. 1997. Biophys . J . 72:1489–1500). Because R368 and R371 are involved in the conformational changes that accompany vol...
متن کاملElectrostatic interactions of S4 voltage sensor in shaker K+ channel
The S4 segment comprises part of the voltage sensor in Shaker K+ channels. We have used a strategy similar to intragenic suppression, but without a genetic selection, to identify electrostatic interactions of the S4 segment that may be important in the mechanism of voltage-dependent activation. The S4 neutralization mutations K374Q and R377Q block maturation of the protein, suggesting that they...
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Invasive mechanical ventilation is a lifesaving intervention for patients with respiratory failure. The most commonly used modes of mechanical ventilation are assist-control, synchronized intermittent mandatory ventilation, and pressure support ventilation. When employed as a diagnostic tool, the ventilator provides data on the static compliance of the respiratory system and airway resistance. ...
متن کاملVoltage-Dependent Structural Interactions in the Shaker K+ Channel
Using a strategy related to intragenic suppression, we previously obtained evidence for structural interactions in the voltage sensor of Shaker K(+) channels between residues E283 in S2 and R368 and R371 in S4 (Tiwari-Woodruff, S.K., C.T. Schulteis, A.F. Mock, and D. M. Papazian. 1997. Biophys. J. 72:1489-1500). Because R368 and R371 are involved in the conformational changes that accompany vol...
متن کاملMechanical behaviors of Flutter VRP1, Shaker, and Acapella devices.
BACKGROUND Flutter VRP1, Shaker, and Acapella are devices that combine positive expiratory pressure (PEP) and oscillations. OBJECTIVES To compare the mechanical performance of the Flutter VRP1, Shaker, and Acapella devices. METHODS An experimental platform and a ventilator, used a flow generator at 5, 10, 15, 20, 26, and 32 L/min, were employed at angles of -30°, 0°, and +30° to evaluate Fl...
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ژورنال
عنوان ژورنال: Shock and Vibration
سال: 1997
ISSN: 1070-9622,1875-9203
DOI: 10.1155/1997/190274